Medications for the treatment of conditions such as skin diseases, skin irritation, bite, fungal infections, etc. are typically produced as cream or ointment because it is an effective way to deliver the drug directly to the body.
The raw materials needed can be as water emulsions in oil or oil in water, consisting of waxes, softeners and lubricants in an oil phase or in a water phase containing emulsifying, stabilizing, thickening materials, materials Prepare and in some cases color. The active ingredients are scattered at each stage or are added when the emulsion is formed.
Production process
The ingredients, formulations and viscosity of the products are widely different, however, a conventional production process is divided into four separate operations:
Preparation of oil phase. Powder ingredients, which sometimes dry before the process begins, are scattered in mineral oil or silicone oil. Heating may be needed to melt some materials.
Scattering of water phase ingredients. Concentrates and stabilizers are dissolved in a separate container in water. Heating may be necessary to accelerate the process.
Emulsion formation. Two phases are mixed with high speed hemorrhoids to form emulsion.
Distribution of active substance. The active ingredient often forms only a small portion of the formulation. To maximize the efficiency and effectiveness of the product, it must be properly scattered.
Production challenges
Using regular mixers you will have a number of problems:
- By adding water, thickening, stabilizing and emulsifying materials can form pellets that mixers cannot break down.
- Similarly, the oil phase ingredients can form masses that require stress for dispersion.
- The ingredients to obtain the viscosity needed and the development of performance must be completely hydrated.
- The materials that are not completely dissolved are attached to the tank wall and parts of the mixer.
- Mixers cannot reduce the particle size enough to stabilize the emulsion.
- Active material can be temperature -sensitive. The cooling of the product before adding active ingredients increases the process time.
- Poor dispersal of active ingredients disrupts the effectiveness of the product.
- To obtain a uniform and sustainable end product, additional time and equipment are required.
Solution provided by ArkanFelez Company
The vacuum of the metal -based hemorgic compound can quickly dissolve solids in liquids, break down thickening, stabilizing and bullets, and completely reduce the size of the particles to make emulsion and suspension stable. The mixing time decreases dramatically, while the uniformity and consistency of the product improve greatly.
- Sustainable emulsion
- Mix without bubbles
- Reduces the mixture of the mix dramatically.
- The performance of the raw materials as thickening materials maximizes and other materials are completely scattered.
- The initial mixing stage of the powder material can be removed.
- The water phase can be produced at ambient temperature and reduced heating costs. It also accelerates the cooling of the mix and reduces time and cost of the process.
- The quality and repeat of the product